1 00:00:08,049 --> 00:00:11,678 [narrator] The story of humans is really a story of extraction. 2 00:00:13,430 --> 00:00:18,184 Take copper, which we learned to mine and hammer into plows and tools, 3 00:00:18,268 --> 00:00:20,478 and mix with tin to make bronze. 4 00:00:21,855 --> 00:00:23,648 Or coal and petroleum, 5 00:00:23,732 --> 00:00:26,067 which allowed us to tame fire. 6 00:00:26,985 --> 00:00:29,237 But in order to shape the world, 7 00:00:29,320 --> 00:00:31,573 first we needed to survive it, 8 00:00:31,656 --> 00:00:35,452 and for that, the most precious resource was this. 9 00:00:36,453 --> 00:00:37,620 Sugar, 10 00:00:37,704 --> 00:00:40,540 the closest thing we have to pure energy. 11 00:00:40,623 --> 00:00:43,877 Think of our ancestors. They were hunters and gatherers. 12 00:00:43,960 --> 00:00:47,422 And for them, sugar was one of the fastest sources of energy. 13 00:00:47,505 --> 00:00:51,134 So we evolved to crave sugar and, when we found it, to eat it. 14 00:00:52,052 --> 00:00:54,262 [narrator] But they weren't eating sugar like this. 15 00:00:54,763 --> 00:00:56,973 It was just found in other foods. 16 00:00:57,057 --> 00:01:00,143 Fruits and vegetables, and tough stalks of sugarcane. 17 00:01:00,226 --> 00:01:05,315 It was over a thousand years ago that some enterprising humans 18 00:01:05,398 --> 00:01:09,819 learned to extract the sugar out of the sugarcane, 19 00:01:09,903 --> 00:01:12,530 evaporate it, crystallize it. 20 00:01:13,156 --> 00:01:16,493 [narrator] And turn it into an ingredient that you could add to anything. 21 00:01:16,576 --> 00:01:17,869 And we did. 22 00:01:18,328 --> 00:01:22,040 [Long] Now we could get the white stuff straight up whenever we wanted. 23 00:01:22,123 --> 00:01:23,458 Problem was, 24 00:01:23,541 --> 00:01:27,295 we still had the Neanderthal brain and Neanderthal body 25 00:01:27,378 --> 00:01:31,299 now living in a tech 2.0, sugar 5.0 environment. 26 00:01:31,382 --> 00:01:33,676 And our bodies and brains can't keep up with that. 27 00:01:34,260 --> 00:01:37,222 [narrator] The calories that were once vital to our survival 28 00:01:37,305 --> 00:01:39,265 are now a public health menace. 29 00:01:39,349 --> 00:01:42,060 [reporter] Sugar is responsible for the high rates of obesity, 30 00:01:42,143 --> 00:01:45,563 diabetes, heart disease and cancer, and should be regulated. 31 00:01:45,647 --> 00:01:47,398 Sugary drink consumption 32 00:01:47,482 --> 00:01:50,902 is a key driver of the obesity epidemic in the United States. 33 00:01:50,985 --> 00:01:51,945 Sugar is addictive. 34 00:01:52,028 --> 00:01:54,697 We're literally poisoning ourselves with sugar. 35 00:01:54,781 --> 00:01:57,325 [narrator] So scientists have been on a quest 36 00:01:57,408 --> 00:02:00,203 to create something that can do what sugar does. 37 00:02:00,286 --> 00:02:02,580 Give us that sweetness and pleasure, 38 00:02:02,664 --> 00:02:05,500 but without all the calories we no longer need. 39 00:02:05,583 --> 00:02:09,963 We sometimes forget that sugar is not just sweetness. 40 00:02:10,046 --> 00:02:12,423 Sugar is energy. 41 00:02:12,507 --> 00:02:15,260 Sugar is happiness. 42 00:02:15,343 --> 00:02:17,345 Sugar is mouthfeel. 43 00:02:17,428 --> 00:02:20,765 Sugar is many, many things in food 44 00:02:20,849 --> 00:02:22,934 and replacing it… 45 00:02:23,017 --> 00:02:25,436 I mean, can you replace the heart? 46 00:02:26,521 --> 00:02:30,400 [narrator] So can we satisfy our deep, ancient craving for sugar 47 00:02:30,483 --> 00:02:31,985 without harming ourselves? 48 00:02:32,652 --> 00:02:35,738 Can we actually have our cake and eat it too? 49 00:02:40,076 --> 00:02:41,786 [man 1] It's coated with golden sugar. 50 00:02:41,870 --> 00:02:43,788 [boy 1] Too good for leprechauns. 51 00:02:43,872 --> 00:02:45,623 [boy 2] Silly rabbit. Trix are for kids. 52 00:02:45,707 --> 00:02:48,251 [man 2] Sugar doesn’t have any nutritional value whatsoever. 53 00:02:48,334 --> 00:02:50,712 I'd argue that you couldn’t even call it a nutrient. 54 00:02:50,795 --> 00:02:52,630 [man 3] Some sugar is converted into fat. 55 00:02:53,214 --> 00:02:57,385 [man 4] He shouldn’t let candy and sweets substitute for other foods. 56 00:02:57,927 --> 00:02:59,429 My tummy wants some yummy. 57 00:03:12,734 --> 00:03:14,944 [Russell] These are sugar sculptures. 58 00:03:15,695 --> 00:03:19,199 Elaborate scenes constructed entirely of sugar, 59 00:03:19,282 --> 00:03:21,492 sometimes over 20 feet high, 60 00:03:21,576 --> 00:03:23,870 displayed at medieval royal banquets. 61 00:03:25,413 --> 00:03:27,165 They were known as subtleties, 62 00:03:27,248 --> 00:03:30,627 because they were a subtle statement of wealth and power. 63 00:03:31,711 --> 00:03:33,171 But it wasn't that subtle. 64 00:03:34,255 --> 00:03:37,091 Sugar was really expensive and rare. 65 00:03:38,551 --> 00:03:41,304 That all changed about 150 to 200 years ago, 66 00:03:41,387 --> 00:03:44,933 when we started being able to distill beet sugar and cane sugar 67 00:03:45,016 --> 00:03:47,518 into very highly processed, highly concentrated sugar. 68 00:03:48,436 --> 00:03:50,605 [Russell] It was no longer a symbol of power. 69 00:03:51,189 --> 00:03:54,943 Sugar was an energy food for health and strength. 70 00:03:56,236 --> 00:04:01,157 Physicians excitedly reported on its unexpected stimulating properties. 71 00:04:01,241 --> 00:04:05,078 Fashionable ladies were encouraged to sip sugary cordials, 72 00:04:05,161 --> 00:04:09,040 the only healthy beverage that can be safely taken after cycling. 73 00:04:09,666 --> 00:04:12,710 And soldiers marveled that it acted like a charm, 74 00:04:12,794 --> 00:04:15,296 relieving fatigue and quenching thirst. 75 00:04:16,047 --> 00:04:19,008 Nobody was looking for something to replace sugar. 76 00:04:19,092 --> 00:04:21,552 It happened entirely by accident. 77 00:04:24,138 --> 00:04:26,391 One evening in 1878, 78 00:04:26,474 --> 00:04:28,810 a research chemist sat down for dinner, 79 00:04:28,893 --> 00:04:32,397 bit into a bread roll, and tasted something sweet. 80 00:04:32,480 --> 00:04:34,190 It wasn't the bread. 81 00:04:34,274 --> 00:04:35,942 It was his fingers. 82 00:04:36,025 --> 00:04:39,279 He'd spilled a solution all over his hands earlier that day. 83 00:04:40,571 --> 00:04:44,701 It was a coal tar derivative, which we now know as saccharin, 84 00:04:44,784 --> 00:04:48,621 300 times sweeter than sugar and zero calories, 85 00:04:48,705 --> 00:04:52,208 which would end up filling those pink packets of Sweet'N Low. 86 00:04:52,292 --> 00:04:55,003 At the time, though, its biggest customers 87 00:04:55,086 --> 00:04:58,798 were diabetics and canners looking for a cheap preservative. 88 00:04:59,924 --> 00:05:04,095 But then, Americans' consumption of sugar started shooting up. 89 00:05:04,178 --> 00:05:07,307 It dipped during the world wars when sugar was rationed, 90 00:05:07,390 --> 00:05:09,058 but quickly recovered. 91 00:05:09,642 --> 00:05:12,562 And Americans' waistlines shot up too, 92 00:05:12,645 --> 00:05:14,230 as did the number of heart attacks. 93 00:05:15,106 --> 00:05:16,649 By the 1960s, 94 00:05:16,733 --> 00:05:21,029 heart disease was responsible for a third of all American deaths. 95 00:05:22,322 --> 00:05:25,908 Doctors started suspecting that sugar might play a role, 96 00:05:25,992 --> 00:05:28,578 and lots of Americans were looking to cut back. 97 00:05:29,370 --> 00:05:32,957 Fortunately, lab safety still wasn’t that great, 98 00:05:33,041 --> 00:05:37,295 so scientists continued to stumble upon new substances that could replace it. 99 00:05:37,795 --> 00:05:40,715 In the 1930s, a drug researcher on a smoke break 100 00:05:40,798 --> 00:05:44,719 happened to taste his fingers and discovered cyclamate, 101 00:05:45,345 --> 00:05:48,598 less sweet than saccharin, but still sweeter than sugar, 102 00:05:48,681 --> 00:05:51,726 which gave us the first no-calorie soda. 103 00:05:51,809 --> 00:05:54,896 [announcer] Yes, there's a party in every bottle of No-Cal, 104 00:05:54,979 --> 00:05:58,232 the first, the finest sugar-free soft drink. 105 00:05:59,192 --> 00:06:01,027 [Russell] Then, in the 1960s, 106 00:06:01,110 --> 00:06:05,531 another drug researcher licked his fingers and tasted something sweet. 107 00:06:05,615 --> 00:06:07,492 [interviewer] Does that happen a lot? 108 00:06:07,575 --> 00:06:10,745 Do scientists just forget to wash their hands and lick them? 109 00:06:10,828 --> 00:06:12,747 [laughs] Not anymore. 110 00:06:12,830 --> 00:06:14,415 [Russell] But thanks to that guy, 111 00:06:14,499 --> 00:06:17,835 we got aspartame, roughly the same calories as sugar, 112 00:06:17,919 --> 00:06:20,755 but 200 times sweeter, so you needed much less. 113 00:06:21,923 --> 00:06:23,925 And then, in the 1970s, 114 00:06:24,008 --> 00:06:27,345 a scientist was working on a compound of sugar and chlorine, 115 00:06:27,428 --> 00:06:30,223 and was reportedly asked to test it. 116 00:06:30,306 --> 00:06:33,226 He misheard and tasted it instead. 117 00:06:33,851 --> 00:06:37,480 The researcher survived, and we got sucralose. 118 00:06:37,563 --> 00:06:39,816 Zero calories, unbelievably sweet, 119 00:06:39,899 --> 00:06:42,527 and marketed as the ultimate substitute. 120 00:06:42,610 --> 00:06:44,362 [man] Splenda brand sweetener. 121 00:06:44,445 --> 00:06:47,323 You can say sugar or you can say Splenda. 122 00:06:48,449 --> 00:06:51,327 [Russell] Artificial sweeteners seemed like a magic trick. 123 00:06:51,953 --> 00:06:53,704 Thanks to the wonders of chemistry… 124 00:06:53,788 --> 00:06:55,873 [woman] You can enjoy all these sweet sensations 125 00:06:55,957 --> 00:06:57,625 without all the calories. 126 00:06:57,708 --> 00:06:59,419 [Russell] Guilt-free pleasure. 127 00:06:59,502 --> 00:07:01,796 [man] Sounds just too good to be true. 128 00:07:03,464 --> 00:07:06,968 [Russell] For many, that did indeed sound too good to be true. 129 00:07:07,635 --> 00:07:10,430 In a couple studies in the '60s and '70s, 130 00:07:10,513 --> 00:07:12,473 they gave rats bladder tumors, 131 00:07:12,557 --> 00:07:16,018 leading to a panic that these sweeteners caused cancer. 132 00:07:16,102 --> 00:07:18,604 The US banned cyclamate, 133 00:07:18,688 --> 00:07:20,690 put a pause on approving aspartame, 134 00:07:20,773 --> 00:07:23,359 and made saccharin products add a warning label 135 00:07:23,443 --> 00:07:25,987 saying it may be hazardous to your health. 136 00:07:26,654 --> 00:07:29,574 To many, sugar seemed like a safer option. 137 00:07:30,366 --> 00:07:33,327 And the sugar industry had done a lot of damage control, 138 00:07:33,411 --> 00:07:35,705 claiming sugar was actually a diet food, 139 00:07:35,788 --> 00:07:38,207 the smart way to stay slim and trim. 140 00:07:38,916 --> 00:07:41,419 Anytime you were tempted to overeat, 141 00:07:41,502 --> 00:07:44,046 sugar could instantly curb your appetite 142 00:07:44,130 --> 00:07:46,799 because it was only 18 calories a teaspoon 143 00:07:46,883 --> 00:07:48,468 and all energy. 144 00:07:49,093 --> 00:07:52,972 This Domino ad even claimed that three spoonfuls of sugar 145 00:07:53,055 --> 00:07:55,558 was less fattening than an apple. 146 00:07:55,641 --> 00:08:00,354 But while it might have fewer calories, not all calories are created equal. 147 00:08:01,772 --> 00:08:05,776 When you eat an apple, your blood sugar levels rise gently. 148 00:08:05,860 --> 00:08:08,070 [Long] You get the sugar, but you also get it 149 00:08:08,154 --> 00:08:11,491 with fiber and water, and a whole host of macronutrients. 150 00:08:12,325 --> 00:08:14,619 [Russell] Which takes a while to digest. 151 00:08:14,702 --> 00:08:18,998 But pure sugar is more instant energy, followed by a crash, 152 00:08:19,081 --> 00:08:22,126 so you can actually feel hungrier than you did before. 153 00:08:22,210 --> 00:08:24,128 And if you eat more and more, 154 00:08:24,212 --> 00:08:27,131 all that instant energy can start to strain your body. 155 00:08:27,215 --> 00:08:30,885 That means your insulin responds by staying chronically elevated as well. 156 00:08:31,636 --> 00:08:35,348 [Russell] Insulin is the hormone that tells your body what to do with sugar, 157 00:08:35,431 --> 00:08:38,476 unlocking your cells so they can use it as energy. 158 00:08:38,559 --> 00:08:43,272 And if they have enough, you store the energy for later as fat. 159 00:08:43,356 --> 00:08:46,609 But if insulin is constantly pumping through your body, 160 00:08:46,692 --> 00:08:50,321 your cells start becoming resistant to it and eventually… 161 00:08:50,404 --> 00:08:55,034 The pancreas is pumping out lots and lots of insulin, 162 00:08:55,117 --> 00:08:57,787 but the insulin's not working. 163 00:08:58,329 --> 00:09:01,082 That's when you get the type 2 diabetes. 164 00:09:01,165 --> 00:09:03,793 [Russell] Your cells can't get the fuel they need. 165 00:09:03,876 --> 00:09:07,672 Unfortunately, this high insulin level 166 00:09:07,755 --> 00:09:12,802 is still working at some of the other jobs insulin is supposed to do. 167 00:09:12,885 --> 00:09:15,304 And one of those is fat-making. 168 00:09:16,013 --> 00:09:19,183 [Russell] So it's easier to gain weight and harder to lose it, 169 00:09:19,267 --> 00:09:21,435 and your blood sugar also builds up, 170 00:09:21,519 --> 00:09:24,564 which can damage parts of your body, like your heart. 171 00:09:26,983 --> 00:09:30,319 Back in the '60s and '70s, that wasn't well-known. 172 00:09:30,403 --> 00:09:33,698 We were getting a lot of mixed messages on sugar, 173 00:09:33,781 --> 00:09:36,659 but we got one message very clearly. 174 00:09:37,410 --> 00:09:41,414 The culprit behind our scourge of heart disease was saturated fat. 175 00:09:42,707 --> 00:09:44,792 The food industry responded 176 00:09:44,875 --> 00:09:48,337 with all kinds of products labeled "fat-free" 177 00:09:48,421 --> 00:09:49,964 or "heart healthy." 178 00:09:50,047 --> 00:09:53,884 But when you take out fat, you lose flavor. 179 00:09:53,968 --> 00:09:55,595 So, in many cases, 180 00:09:55,678 --> 00:09:58,139 companies added sugar in its place. 181 00:09:59,098 --> 00:10:02,685 But artificial sweeteners were also recovering their reputation. 182 00:10:03,269 --> 00:10:05,563 Study after study after study 183 00:10:05,646 --> 00:10:08,983 hadn't found any evidence that they cause cancer in humans. 184 00:10:09,692 --> 00:10:11,944 The rats in those earlier studies? 185 00:10:12,028 --> 00:10:16,324 They were given the equivalent of hundreds of cans of diet soda a day. 186 00:10:17,033 --> 00:10:18,034 And also… 187 00:10:18,117 --> 00:10:20,328 Rats and mice aren't humans. 188 00:10:20,411 --> 00:10:25,416 [Russell] When Coca-Cola released an aspartame-based soda in 1983, 189 00:10:25,499 --> 00:10:27,209 it was a landmark event. 190 00:10:27,293 --> 00:10:29,712 [man] The world premiere of Diet Coke. 191 00:10:30,463 --> 00:10:34,008 ♪ You’re gonna drink it Just for the taste of it ♪ 192 00:10:35,259 --> 00:10:39,764 [Russell] Within a decade, aspartame had replaced over a billion pounds of sugar 193 00:10:39,847 --> 00:10:42,016 in foods and drinks in the US. 194 00:10:42,099 --> 00:10:46,062 But artificial sweeteners weren't replacing sugar in our diet. 195 00:10:46,145 --> 00:10:48,731 They were largely an excuse to eat more of it, 196 00:10:49,357 --> 00:10:52,276 and we'd figured out even cheaper ways to make it, 197 00:10:52,360 --> 00:10:53,861 like out of corn. 198 00:10:53,944 --> 00:10:59,033 Sugar is now added to three-quarters of packaged foods in the US, 199 00:10:59,116 --> 00:11:01,911 going by more than 60 different names. 200 00:11:01,994 --> 00:11:04,038 [Long] Dextrose, fructose, sucrose, 201 00:11:04,121 --> 00:11:07,750 high-fructose corn syrup. Anything that ends with “ose” is a form of sugar. 202 00:11:07,833 --> 00:11:11,420 Or one of my favorite euphemisms for sugar, 203 00:11:11,504 --> 00:11:13,756 evaporated cane juice. 204 00:11:13,839 --> 00:11:16,133 [Russell] There was no chance artificial sweeteners 205 00:11:16,217 --> 00:11:18,803 were going to replace sugar in all these foods. 206 00:11:18,886 --> 00:11:21,055 I think anybody who has tried an artificial sweetener 207 00:11:21,138 --> 00:11:23,724 knows that we're not really fooled by them. 208 00:11:23,808 --> 00:11:26,185 They don't taste exactly like sugar. 209 00:11:26,268 --> 00:11:28,979 No, I don't like the way that fake sugar, 210 00:11:29,063 --> 00:11:31,857 you know, leaves that taste in your mouth. 211 00:11:31,941 --> 00:11:34,193 -How bad is it? -Sweetened chemically. 212 00:11:34,276 --> 00:11:36,737 Super sweet that your mouth can’t really handle it. 213 00:11:38,322 --> 00:11:41,158 [man] I'm not a fan of artificial sweeteners. 214 00:11:41,242 --> 00:11:43,536 I’ve had saccharin before in sodas and chewing gum. 215 00:11:43,619 --> 00:11:47,373 It makes my mouth chalky and dry, and needing to drink more water. 216 00:11:48,040 --> 00:11:52,169 [Russell] Pichet Ong has spent his career trying to make desserts with less sugar, 217 00:11:52,253 --> 00:11:54,463 without ever compromising on taste. 218 00:11:54,547 --> 00:11:57,049 When I was consuming the ones with aspartame, 219 00:11:57,133 --> 00:11:59,218 it also had a similar effect to me. 220 00:11:59,301 --> 00:12:02,388 It’s not quite, you know, natural tasting. 221 00:12:03,347 --> 00:12:06,392 [Russell] A big part of how sugar tastes is time. 222 00:12:06,475 --> 00:12:10,646 The time it takes for the sweetness to peak after you take a bite, 223 00:12:10,730 --> 00:12:13,983 how long it lingers, and how fast it declines. 224 00:12:14,608 --> 00:12:17,903 It's called temporal sweetness profile. 225 00:12:17,987 --> 00:12:19,947 This is how it looks for sugar. 226 00:12:20,030 --> 00:12:24,285 It peaks really fast and disappears really fast. 227 00:12:24,368 --> 00:12:27,204 And this is how it looks for sucralose. 228 00:12:27,288 --> 00:12:29,623 The sweet taste comes on slower 229 00:12:29,707 --> 00:12:32,001 and takes its sweet time leaving. 230 00:12:32,710 --> 00:12:36,630 Aspartame hits even later and loiters even longer. 231 00:12:37,381 --> 00:12:39,759 The difference is fractions of a second, 232 00:12:39,842 --> 00:12:42,845 but for our taste buds, that's an eternity. 233 00:12:43,637 --> 00:12:46,223 And sugar is about more than just sweetness. 234 00:12:46,307 --> 00:12:48,100 It makes icing glisten 235 00:12:48,184 --> 00:12:50,853 and cakes moist and fluffy. 236 00:12:50,936 --> 00:12:54,231 [Baniel] If you take all the sugar out of a cake, 237 00:12:54,315 --> 00:12:57,318 the cake would come out like a pita bread. 238 00:12:57,401 --> 00:13:00,780 So the challenges are huge. 239 00:13:00,863 --> 00:13:04,617 The one sweetener that's worked for me in many recipes is stevia. 240 00:13:04,700 --> 00:13:07,745 [Russell] Stevia is a natural calorie-free sweetener. 241 00:13:07,828 --> 00:13:11,582 It comes from a South American plant, and it can make a decent pudding. 242 00:13:12,166 --> 00:13:15,628 But the sweetness comes on even later than artificial sweeteners 243 00:13:15,711 --> 00:13:19,507 and overstays its welcome, revealing itself as fake. 244 00:13:20,549 --> 00:13:24,678 There is one sweetener that tastes uncannily like sugar, 245 00:13:24,762 --> 00:13:26,889 just a little less intense. 246 00:13:26,972 --> 00:13:31,310 Allulose, the rising star of sugar substitutes. 247 00:13:32,228 --> 00:13:34,104 Technically, it's a sugar, 248 00:13:34,188 --> 00:13:38,192 a rare kind found in tiny amounts in foods like figs and raisins, 249 00:13:39,109 --> 00:13:41,737 but it doesn't act like sugar in our bodies. 250 00:13:41,821 --> 00:13:45,825 We can't fully break it down, which makes it nearly calorie-free. 251 00:13:46,408 --> 00:13:48,327 It performs well in the kitchen, 252 00:13:48,410 --> 00:13:50,663 and early studies suggest it's safe. 253 00:13:51,288 --> 00:13:55,084 But only a few producers make it. Most countries haven't approved it yet. 254 00:13:56,293 --> 00:13:59,088 And it's priced like gourmet health food. 255 00:14:00,172 --> 00:14:02,842 And none of these sweeteners, even allulose, 256 00:14:02,925 --> 00:14:05,928 can replace the most magical thing about sugar. 257 00:14:07,513 --> 00:14:12,184 [Long] So sugar acts in the same part of your brain as sex and addictive drugs. 258 00:14:12,268 --> 00:14:14,103 The reward zone of your brain. 259 00:14:14,186 --> 00:14:17,815 So you eat sugar, you've released dopamine, you feel happier. 260 00:14:17,898 --> 00:14:20,943 [Russell] It isn't just hunger that drives us to eat sugar. 261 00:14:21,443 --> 00:14:22,778 It's desire. 262 00:14:23,320 --> 00:14:25,489 That's why, even when we're full, 263 00:14:25,573 --> 00:14:28,701 we still perk up when someone offers us dessert. 264 00:14:28,784 --> 00:14:29,952 [Baniel] Isn't that funny? 265 00:14:30,035 --> 00:14:32,746 We have a special space 266 00:14:32,830 --> 00:14:35,791 for the indulgent taste 267 00:14:35,875 --> 00:14:37,668 at the end of a meal. 268 00:14:38,502 --> 00:14:41,922 [Russell] One study found that the reward zones of our brain 269 00:14:42,006 --> 00:14:45,926 only get activated when sweetness comes with calories. 270 00:14:46,969 --> 00:14:50,014 If you want the pleasure, you have to pay for it. 271 00:14:51,307 --> 00:14:54,268 The bitter truth is we can't mimic sugar, 272 00:14:54,351 --> 00:14:56,854 just leaving out the parts we don't like. 273 00:14:56,937 --> 00:14:59,565 So some people are taking a different approach, 274 00:14:59,648 --> 00:15:02,818 trying to reinvent the sugar crystal itself. 275 00:15:06,155 --> 00:15:08,824 In 2013, at age 95, 276 00:15:08,908 --> 00:15:12,494 Professor Avraham Baniel was reflecting back on his life. 277 00:15:13,370 --> 00:15:17,791 He'd been an industrial chemist and worked on many things over his long career. 278 00:15:17,875 --> 00:15:20,336 Extracting copper from desert sand, 279 00:15:20,419 --> 00:15:22,046 minerals from the Dead Sea, 280 00:15:22,129 --> 00:15:24,465 fertilizers, biofuels, 281 00:15:24,548 --> 00:15:26,300 carpet fiber, citric acid, 282 00:15:26,383 --> 00:15:28,761 and a long stint as a professor. 283 00:15:29,428 --> 00:15:32,681 And he remembered something that happened a long time ago 284 00:15:32,765 --> 00:15:34,850 when he was a young man just starting out. 285 00:15:36,018 --> 00:15:37,853 The world was at war, 286 00:15:37,937 --> 00:15:40,397 and sugar was severely rationed. 287 00:15:40,481 --> 00:15:44,360 There was no sugar, or hardly any sugar, to be had. 288 00:15:44,443 --> 00:15:46,904 [Russell] Professor Baniel is Eran’s father. 289 00:15:47,571 --> 00:15:52,201 At the time, he was working near Haifa, helping the war effort by making bombs. 290 00:15:52,868 --> 00:15:55,621 One day, he got a strange visit from a friend's wife, 291 00:15:55,704 --> 00:15:57,873 who asked if he could get her some starch. 292 00:15:57,957 --> 00:16:00,834 [Baniel] My father said, "Why do you want starch?" 293 00:16:00,918 --> 00:16:02,628 [Russell] It was a trick she knew. 294 00:16:02,711 --> 00:16:05,130 If you made a sticky pudding out of starch 295 00:16:05,214 --> 00:16:07,758 and then added whatever little sugar you have, 296 00:16:07,841 --> 00:16:09,927 it would magically taste sweeter, 297 00:16:10,010 --> 00:16:12,179 as if it had a lot more sugar in it. 298 00:16:12,262 --> 00:16:13,973 [Baniel] So my father thought, 299 00:16:14,056 --> 00:16:16,558 "Funny. I must remember that." 300 00:16:16,642 --> 00:16:18,936 And, of course, he forgot all about it. 301 00:16:19,019 --> 00:16:22,189 [Russell] Until that fateful day in 2013, 302 00:16:22,272 --> 00:16:24,566 when it hit him like a revelation. 303 00:16:24,650 --> 00:16:28,445 So my father said, "The only way to cut sugar 304 00:16:29,405 --> 00:16:32,241 is by using sugar in a different way." 305 00:16:34,243 --> 00:16:36,954 [Russell] You see, sugar has a dirty secret. 306 00:16:37,037 --> 00:16:39,498 You don't actually taste most of it. 307 00:16:40,082 --> 00:16:41,875 When you take a bite of cake, 308 00:16:41,959 --> 00:16:44,461 the sugar crystals dissolve in your mouth, 309 00:16:44,545 --> 00:16:47,464 and the sugar molecules go all over the place. 310 00:16:47,548 --> 00:16:51,135 Only a fraction of them ever touch your taste buds. 311 00:16:51,218 --> 00:16:53,679 The rest? You just swallow it. 312 00:16:53,762 --> 00:16:56,557 It goes where you don't want it. 313 00:16:57,182 --> 00:17:00,060 [Russell] The reason starch made pudding taste sweeter 314 00:17:00,144 --> 00:17:03,063 is that it coats your tongue and makes it stickier, 315 00:17:03,147 --> 00:17:05,607 so more of the sugar hits your taste buds. 316 00:17:06,275 --> 00:17:09,611 Eran's dad thought he had a more efficient solution, 317 00:17:09,695 --> 00:17:12,990 embedding something into the sugar crystal itself, 318 00:17:13,073 --> 00:17:14,408 which would act like… 319 00:17:14,491 --> 00:17:17,911 [Baniel] A sponge for the sugar molecules. 320 00:17:17,995 --> 00:17:21,623 [Russell] Soaking them up and creating a new kind of crystal 321 00:17:21,707 --> 00:17:24,543 containing giant clumps of sugar molecules. 322 00:17:25,753 --> 00:17:29,048 So when you take a bite, and the crystals dissolve, 323 00:17:29,131 --> 00:17:33,052 more of those molecules have a chance to reach our sweet receptors. 324 00:17:34,219 --> 00:17:36,764 Eran was so convinced by his dad's idea, 325 00:17:36,847 --> 00:17:38,557 he started a company. 326 00:17:38,640 --> 00:17:40,267 DouxMatok. 327 00:17:40,350 --> 00:17:42,227 "Doux" is "sweet" in French, 328 00:17:42,311 --> 00:17:44,813 and "matok" is "sweet" in Hebrew. 329 00:17:44,897 --> 00:17:47,399 And "du" also means "double" in Hebrew. 330 00:17:47,483 --> 00:17:50,903 [Baniel] So "sweet sweet" or "double sweet." 331 00:17:51,528 --> 00:17:53,363 [Russell] They discovered that silica, 332 00:17:53,447 --> 00:17:56,283 a common food additive, was a great sponge. 333 00:17:56,867 --> 00:17:58,827 And the result was Incredo, 334 00:17:58,911 --> 00:18:01,080 nearly 100% sugar, 335 00:18:01,163 --> 00:18:04,708 but because we taste more of it, we don't need to eat as much. 336 00:18:05,417 --> 00:18:07,419 It's got a lot of people excited. 337 00:18:07,503 --> 00:18:10,839 Time named it one of the best inventions of 2020. 338 00:18:11,423 --> 00:18:13,425 But it has its limitations, 339 00:18:13,509 --> 00:18:15,302 namely water. 340 00:18:16,011 --> 00:18:20,516 With Incredo, the sugar and the silica break apart as soon as they get wet. 341 00:18:20,599 --> 00:18:22,726 [Baniel] Boom! The couple is broken. 342 00:18:22,810 --> 00:18:25,562 Sugar on one side, carrier on the other side. 343 00:18:25,646 --> 00:18:27,106 The miracle is gone. 344 00:18:28,190 --> 00:18:30,818 [Russell] Our bodies evolved for this compound 345 00:18:30,901 --> 00:18:33,362 in ways that are hard to trick or hack, 346 00:18:34,196 --> 00:18:36,073 and that we still don't fully understand. 347 00:18:37,699 --> 00:18:39,868 But we keep learning more about sugar, 348 00:18:39,952 --> 00:18:43,330 and some common assumptions are due for another update. 349 00:18:44,164 --> 00:18:45,457 In the 2000s, 350 00:18:45,541 --> 00:18:49,336 high-fructose corn syrup was considered the most evil of sugars. 351 00:18:50,003 --> 00:18:52,131 It's been called "the Devil's candy," 352 00:18:52,214 --> 00:18:55,509 a "sinister invention," and "the crack of sweeteners." 353 00:18:56,093 --> 00:18:58,137 But a lot of high-fructose corn syrup 354 00:18:58,220 --> 00:19:01,181 is basically the same molecular structure as sugar. 355 00:19:01,265 --> 00:19:02,766 No better, no worse. 356 00:19:03,475 --> 00:19:05,394 Things like agave nectar and honey 357 00:19:05,477 --> 00:19:08,730 are widely seen as healthier alternatives to sugar, but… 358 00:19:08,814 --> 00:19:13,152 The truth is, whether it's fructose, sucrose, glucose, or the other forms, 359 00:19:13,235 --> 00:19:14,820 your body sees it as sugar. 360 00:19:15,404 --> 00:19:18,448 [Russell] Brown sugar has some trace nutrients that white doesn't, 361 00:19:19,158 --> 00:19:21,201 but we're talking really trace. 362 00:19:22,161 --> 00:19:24,246 Raw sugar isn't better for you, either. 363 00:19:24,329 --> 00:19:26,540 It's not even really raw, 364 00:19:26,623 --> 00:19:28,792 just slightly less refined. 365 00:19:29,501 --> 00:19:31,003 And to be clear, 366 00:19:31,086 --> 00:19:34,298 artificial sweeteners won't give you cancer. 367 00:19:34,882 --> 00:19:36,592 By the early 2000s, 368 00:19:36,675 --> 00:19:40,846 saccharin products were no longer required to carry a warning label. 369 00:19:40,929 --> 00:19:43,390 Compared to a sugar-sweetened beverage, 370 00:19:43,473 --> 00:19:45,851 an aspartame-sweetened beverage 371 00:19:45,934 --> 00:19:48,812 is a much safer, 372 00:19:48,896 --> 00:19:50,439 healthier choice. 373 00:19:50,522 --> 00:19:51,565 And I 374 00:19:52,649 --> 00:19:55,235 will probably go to my grave saying that. 375 00:19:55,819 --> 00:19:57,571 [Russell] But recent studies also suggest 376 00:19:57,654 --> 00:20:00,657 that artificial sweeteners aren't a great way to lose weight, 377 00:20:01,325 --> 00:20:05,495 possibly because they change the composition of bacteria in our guts. 378 00:20:08,123 --> 00:20:10,834 The taste of sweet never comes for free, 379 00:20:10,918 --> 00:20:12,753 but there is some good news. 380 00:20:13,420 --> 00:20:18,008 Sugar actually isn't as bad for us as we may have been led to believe. 381 00:20:18,842 --> 00:20:21,678 You may have heard that sugar makes kids hyper, 382 00:20:21,762 --> 00:20:24,514 but that idea was based on pretty weak data. 383 00:20:25,641 --> 00:20:27,809 Later studies couldn't find any evidence 384 00:20:27,893 --> 00:20:31,271 that sugar affects kids' behavior or cognitive function. 385 00:20:31,980 --> 00:20:34,858 Very often these days, 386 00:20:34,942 --> 00:20:36,818 someone will say, 387 00:20:36,902 --> 00:20:39,696 “Sugar is the new tobacco, 388 00:20:40,280 --> 00:20:42,115 and we should banish it.” 389 00:20:42,199 --> 00:20:45,244 [Russell] You may have heard that sugar's wildly addictive. 390 00:20:45,327 --> 00:20:47,829 The science is coming in now where we know 391 00:20:47,913 --> 00:20:51,083 that sugar is more addictive than cocaine. 392 00:20:51,166 --> 00:20:52,751 Eight times more addictive than cocaine. 393 00:20:52,834 --> 00:20:54,753 Addictive like heroin, rock cocaine. 394 00:20:54,836 --> 00:20:58,674 [Russell] But that evidence, once again, comes from mice studies. 395 00:20:59,508 --> 00:21:02,052 If you had to pick between sugar withdrawal 396 00:21:02,135 --> 00:21:03,929 and cocaine withdrawal, 397 00:21:04,012 --> 00:21:05,806 definitely pick sugar. 398 00:21:05,889 --> 00:21:08,850 [Stanhope] Clearly, there's a greater level 399 00:21:08,934 --> 00:21:11,520 of addiction 400 00:21:11,603 --> 00:21:16,316 and physiological effect with cocaine compared to the sugar. 401 00:21:20,862 --> 00:21:22,823 [Long] As I always say, "Sugar isn't poison." 402 00:21:22,906 --> 00:21:24,533 "The dose makes the poison." 403 00:21:24,616 --> 00:21:26,618 A little bit of sugar is not the problem. 404 00:21:26,702 --> 00:21:30,122 It is the large, constant, chronic quantities that create the problem. 405 00:21:30,205 --> 00:21:31,290 [Russell] In the US, 406 00:21:31,373 --> 00:21:35,627 sugar consumption has actually been going down for the past two decades. 407 00:21:35,711 --> 00:21:40,841 But fast food and junk food consumption is not going down. 408 00:21:40,924 --> 00:21:44,052 [Russell] So obesity rates keep trending upwards. 409 00:21:44,136 --> 00:21:46,430 People are still eating 410 00:21:46,972 --> 00:21:51,768 horrifyingly little amounts of fresh fruit and vegetable, 411 00:21:52,519 --> 00:21:54,896 whole grains, beans. 412 00:21:54,980 --> 00:21:56,690 Nobody eats beans. 413 00:21:57,983 --> 00:22:00,819 [Russell] We may never be able to have our cake and eat it too. 414 00:22:01,528 --> 00:22:03,697 That's just not how cakes work. 415 00:22:04,239 --> 00:22:07,492 But we're getting closer to making healthier cakes. 416 00:22:08,160 --> 00:22:10,954 On November 27th, 2020, 417 00:22:11,038 --> 00:22:15,042 Eran's father celebrated his 102nd birthday. 418 00:22:15,125 --> 00:22:17,794 He's eating a brownie. 419 00:22:17,878 --> 00:22:20,922 The sugar was 35% reduced. 420 00:22:21,006 --> 00:22:22,591 I mean, he loved it. 421 00:22:22,674 --> 00:22:26,303 He was really beside himself with happiness. 422 00:22:26,803 --> 00:22:29,181 Mazel tov! 423 00:22:29,264 --> 00:22:32,684 [Russell] We should all be aiming for a more balanced diet 424 00:22:32,768 --> 00:22:34,936 without too much sugar. 425 00:22:35,020 --> 00:22:37,481 But declaring war on a single ingredient 426 00:22:37,564 --> 00:22:39,733 is a recipe for defeat. 427 00:22:39,816 --> 00:22:43,528 You're not going to stick to any diet that makes you miserable. 428 00:22:44,279 --> 00:22:48,283 Dark chocolate, especially dark chocolate bars with nuts in them. 429 00:22:48,367 --> 00:22:51,787 That, without a doubt, is my most favorite. 430 00:22:52,621 --> 00:22:55,749 [Ong] It makes me feel energetic and happy. 431 00:22:55,832 --> 00:22:57,084 When I go to bed at night, 432 00:22:57,167 --> 00:22:59,795 I will be thinking I can't wait to wake up and have some dessert. 433 00:23:00,754 --> 00:23:04,424 We need to cut the overconsumption of sugar. 434 00:23:04,508 --> 00:23:06,009 Absolutely. 435 00:23:06,093 --> 00:23:07,928 But the overconsumption, 436 00:23:08,512 --> 00:23:12,099 not the essential consumption of sugar.